Pick a good time
If you can, pick a time to take the second medicine when you’ve had a good meal, plenty of rest, and can be in a comfortable, private place where you can rest.
Get over-the-counter help
Before you take the second medicine (misoprostol), we recommend taking over the counter pain medicine, like ibuprofen (Advil or Motrin). This helps with pain and bleeding. Placing a heating pad on your belly can also help.